1. Daria -- God! I loved this show. It was funny, poked very appropriate fun at the ridiculousness of high schoolers, and kinda perfectly captured that early-90s, "alternative" period that was a big chunk of my adolescence.
Favorite characters: Daria (of course), Trent, Mr. Morgendorffer
2. Home Movies -- One of the most consistently hilarious shows to have ever seen the light of day. Brendon Small and company remain some of the most endearing, ridiculous and memorable characters of all time. To this day, when I hear a character voiced by H. Jon Benjamin, I yell, "Hey, that's Coach McGuirk!" The music was pretty awesome. Also, Shannon is the greatest bully ever.
Favorite characters: Coach McGuirk, Brendon, Shannon, the gentle talk therapist, Walter & Perry. (I pretty much love every character here.)
3. The Venture Bros. -- I'm lamenting the lack of Brock Samson and mourning the loss of 24 on the latest season, but I still carry quite a torch for Rusty Venture and company. Love the whole parody of the superheroes milieu. Just plain funny.
Favorite characters: Brock Samson, Dr. Orpheus, the Monarch
4. Garfield and Friends -- Best theme song ever! (The first one.) Damn good Saturday morning cartooning here. Looking back, I'm surprised at the level of humor. This was a show for kids, but I still crack up thinking about the general wackyness.
Favorite characters: Garfield, Pooky, Binky the Clown
5. Laff-A-Lympics -- Everyone watched Hanna Barbera cartoons. Everyone. And when HB decided to put all their stars together, it got that much more exciting.